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Home/Compounds/Pharmaceutical Intermediate/Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, monophenyl ester
C15H18N5O4P
363.31 g/mol
Pharmaceutical Intermediate

Phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

CAS379270-35-6EC807-851-4
Category
Pharmaceutical Intermediate
Compound Class
Organic Acid
Primary Use
Pharmaceutical Intermediate

This compound is a phosphonate intermediate specifically designed for the synthesis of antiviral prodrugs. Its structure features a purine base and a phosphonate ester group, which are key to its role in pharmaceutical manufacturing.

Phosphonate intermediate for antiviral prodrugsRaw material for pharmaceutical synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.83

Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, diphenyl ester

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SimilarStructure SimilarSimilarity 0.74

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Referencesame scaffold

Tenofovir alafenamide

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pharmaceutical raw material

Identifiers
IUPAC Name

[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphinic acid

InChIKey

ITAMCOCNZJPJDF-LLVKDONJSA-N

SMILES

C[C@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(O)OC3=CC=CC=C3

Synonyms (15)
  • Monophenylester
  • Tenofovir Impurity 115
  • Tenofovir Impurity 26