C21H29N6O5P
476.5 g/mol
APIDanger
TENOFOVIR ALAFENAMIDE
CAS379270-37-8
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material
Tenofovir alafenamide is a prodrug of tenofovir, a reverse transcriptase inhibitor used in antiviral therapy. It is a phosphoramidate ester derivative formulated for pharmaceutical manufacturing as an active pharmaceutical ingredient.
Active pharmaceutical ingredient in combination therapy for HIV-1 infection
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
StrongSame Parent
Tenofovir alafenamide fumarate
CAS1392275-56-7
antiviral prodrug for HIV-1
ReferenceSame Category
Sulfamonomethoxine sodium
CAS38006-08-5
pharmaceutical raw material
ReferenceSame Category
Climbazole
CAS38083-17-9
pharmaceutical raw material
ReferenceSame Category
Bosutinib
CAS380843-75-4
pharmaceutical raw material
ReferenceSame Category
11-hydroxy-N-methyldesloratadine
CAS38089-93-9
pharmaceutical raw material
Referencestereoisomer of
Isopropyl ((r)-((((r)-1-(6-amino-9h-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-l-alaninate
CAS383365-04-6
pharmaceutical raw material
Referencestereoisomer of
Isopropyl ((s)-((((r)-1-(6-amino-9h-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-d-alaninate
CAS2053424-82-9
pharmaceutical intermediate
Referencestereoisomer of
Isopropyl ((r)-((((r)-1-(6-amino-9h-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-d-alaninate
CAS2053424-88-5
research compound
Safety Reference
Danger
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation
Customs Tariff Classification
The international HS code for TENOFOVIR ALAFENAMIDE (CAS 379270-37-8) is 2933.59.
HS code (international, 6-digit)
2933.59
EU CN code (8-digit)
2933 59 95
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
propan-2-yl (2S)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate
InChIKey
LDEKQSIMHVQZJK-CAQYMETFSA-N
SMILES
C[C@H](CN1C=NC2=C(N=CN=C21)N)OC[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)OC3=CC=CC=C3
Synonyms (24)
- Tenofovir alafenamide (USAN/INN)
- GS-7340 Tenofovir alafenamide
- GS-7340?
- TENOFOVIR ALAFENAMIDE
- TFV Alafenamide
- Tenofovir alafenamida
- US12049474, Compound TAF
- Vemlidy
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