C6H5ClFN
145.56 g/mol
Pharmaceutical IntermediateDanger
3-CHLORO-4-FLUOROANILINE
CAS367-21-5EC206-682-8
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate
3-Chloro-4-fluoroaniline is a chemical compound used as a pharmaceutical intermediate, primarily in the synthesis of active pharmaceutical ingredients. Its structure includes an amine group attached to an aromatic ring bearing both chlorine and fluorine substituents, contributing to its utility in medicinal chemistry.
Pharmaceutical intermediate for API synthesisBuilding block for haloaromatic compounds
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
ReferenceSame Category
4-chloro-3-fluoroaniline
CAS367-22-6
pharmaceutical intermediate
ReferenceSame Category
4-Bromo-2-fluoroaniline
CAS367-24-8
pharmaceutical intermediate
ReferenceSame Category
2,4-difluoroaniline
CAS367-25-9
pharmaceutical intermediate
ReferenceSame Category
2,4-Difluorophenol
CAS367-27-1
pharmaceutical intermediate
Safety Reference
Danger
H301Toxic if swallowed
H302Harmful if swallowed
H311Toxic in contact with skin
H318Causes serious eye damage
H331Toxic if inhaled
H373May cause damage to organs through prolonged or repeated exposure
Customs Tariff Classification
The international HS code for 3-CHLORO-4-FLUOROANILINE (CAS 367-21-5) is 2921.42.
HS code (international, 6-digit)
2921.42
EU CN code (8-digit)
2921 42 00
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
3-chloro-4-fluoroaniline
InChIKey
YSEMCVGMNUUNRK-UHFFFAOYSA-N
SMILES
C1=CC(=C(C=C1N)Cl)F
Synonyms (15)
- C104
- 3-CHLORO-4-FLUOROANILINE
- 3-Chloro-4-fluoroanilin
- 3-Chloro-4-fluorobenzenamine
- 3-Chloro-4-fluorophenylamine
- 3-chloro-4-flouroaniline
- 4-FLUORO-3-CHLOROANILINE
- 4-fluoro-3-chlorophenylamine
- Aniline, 3-chloro-4-fluoro-
- Gefitinib Impurity 36
- Gefitinib Impurity V
- M-CHLORO-P-FLUOROANILINE
- Norfloxacin Intermediates
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