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Home/Compounds/Pharmaceutical Intermediate/4-chloro-3-fluoroaniline
C6H5ClFN
145.56 g/mol
Pharmaceutical IntermediateDanger

4-Chloro-3-fluoroaniline

CAS367-22-6EC206-683-3
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate

4-Chloro-3-fluoroaniline is a chemical compound used as a pharmaceutical intermediate. It features an aromatic ring substituted with chlorine and fluorine atoms, along with an amine group.

pharmaceutical intermediateresearch compound

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

4-Bromo-2-fluoroaniline

CAS367-24-8

pharmaceutical intermediate

ReferenceSame Category

2,4-difluoroaniline

CAS367-25-9

pharmaceutical intermediate

ReferenceSame Category

2,4-Difluorophenol

CAS367-27-1

pharmaceutical intermediate

ReferenceSame Category

5-Fluoro-2-methylaniline

CAS367-29-3

pharmaceutical intermediate

Safety Reference

Toxic
Toxic
Harmful
Harmful
Danger
H302Harmful if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H332Harmful if inhaled
H335May cause respiratory irritation

Customs Tariff Classification

The international HS code for 4-Chloro-3-fluoroaniline (CAS 367-22-6) is 2921.42.

HS code (international, 6-digit)

2921.42

EU CN code (8-digit)

2921 42 00

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

4-chloro-3-fluoroaniline

InChIKey

ACMJJQYSPUPMPN-UHFFFAOYSA-N

SMILES

C1=CC(=C(C=C1N)F)Cl

Synonyms (10)
  • 3-Fluoro-4-Chloroaniline
  • 4-Chloro-3-fluoroaniline
  • 4-Chloro-3-fluoroanline
  • 4-chloro-3-fluorobenzenamine
  • 4-chloro-3-fluorophenylamine
  • Aniline, 4-chloro-3-fluoro-
  • Gefitinib Impurity 44

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