C21H23NO4
353.4 g/mol
Pharmaceutical IntermediateWarning
Fmoc-leucine
CAS35661-60-0EC252-662-7
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate
Fmoc-leucine is a protected amino acid derivative used in solid-phase peptide synthesis. Its fluorenylmethoxycarbonyl (Fmoc) group shields the amino terminus during chain assembly.
Protected amino acid for peptide synthesisBuilding block in chemical and peptide syntheses
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 35661-60-0
Related Compounds
SimilarStructure SimilarSimilarity 0.73
Fmoc-L-cysteine
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pharmaceutical intermediate
ReferenceSame Category
2H-1-Benzopyran-2-one, 3-(2-benzoxazolyl)-7-(diethylamino)-
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pharmaceutical intermediate
Referencestereoisomer of
Fmoc-D-leucine
CAS114360-54-2
pharmaceutical intermediate
Safety Reference
Warning
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
Identifiers
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid
InChIKey
CBPJQFCAFFNICX-IBGZPJMESA-N
SMILES
CC(C)C[C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Synonyms (26)
- FMOC-LEU
- Fmoc-L-Leu
- Fmoc-L-Leu-OH
- Fmoc-L-leucine
- Fmoc-Leu-OH
- Fmoc-N-Me-D-Nva-OH
- N-.alpha.-Fmoc-L-leucine
- N-Fmoc leucine
- N-Fmoc-L-leucine
- fmoc-leucine