C21H23NO4
353.4 g/mol
Pharmaceutical IntermediateWarning
Fmoc-leucine
CAS35661-60-0EC252-662-7
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate
Fmoc-leucine is a protected amino acid derivative used in solid-phase peptide synthesis. Its fluorenylmethoxycarbonyl (Fmoc) group shields the amino terminus during chain assembly.
Protected amino acid for peptide synthesisBuilding block in chemical and peptide syntheses
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
SimilarStructure SimilarSimilarity 0.73
Fmoc-L-cysteine
CAS135248-89-4
pharmaceutical intermediate
ReferenceSame Category
6-Carboxyl-4-phenyl-3,4-dihydrocoumarin
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pharmaceutical intermediate
ReferenceSame Category
7-Chloro-1H-pyrrolo[2,3-c]pyridine
CAS357263-41-3
pharmaceutical intermediate
ReferenceSame Category
Fmoc-beta-Alanine
CAS35737-10-1
pharmaceutical intermediate
ReferenceSame Category
2H-1-Benzopyran-2-one, 3-(2-benzoxazolyl)-7-(diethylamino)-
CAS35773-42-3
pharmaceutical intermediate
Referencestereoisomer of
Fmoc-D-leucine
CAS114360-54-2
pharmaceutical intermediate
Related Reading
Safety Reference
Warning
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
Customs Tariff Classification
The international HS code for Fmoc-leucine (CAS 35661-60-0) is 2924.29.
HS code (international, 6-digit)
2924.29
EU CN code (8-digit)
2924 29 70
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid
InChIKey
CBPJQFCAFFNICX-IBGZPJMESA-N
SMILES
CC(C)C[C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Synonyms (26)
- FMOC-LEU
- Fmoc-L-Leu
- Fmoc-L-Leu-OH
- Fmoc-L-leucine
- Fmoc-Leu-OH
- Fmoc-N-Me-D-Nva-OH
- N-.alpha.-Fmoc-L-leucine
- N-Fmoc leucine
- N-Fmoc-L-leucine
- fmoc-leucine
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