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Home/Compounds/Pharmaceutical Intermediate/L-Glutamic acid di-tert-butyl ester hydrochloride
C13H26ClNO4
295.8 g/mol
Pharmaceutical Intermediate

Di-tert-butyl Glutamate Hydrochloride

CAS32677-01-3
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate

Di-tert-butyl Glutamate Hydrochloride is a salt-like derivative of glutamic acid in which both carboxyl groups are protected by tert-butyl esters. It is primarily used as a building block in solid-phase peptide synthesis, where the protecting groups allow selective formation of peptide bonds without unwanted side reactions.

Building block for solid-phase peptide synthesisPharmaceutical intermediate for the manufacture of peptide-based compounds

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

ditert-butyl (2S)-2-aminopentanedioate;hydrochloride

InChIKey

LFEYMWCCUAOUKZ-FVGYRXGTSA-N

SMILES

CC(C)(C)OC(=O)CC[C@@H](C(=O)OC(C)(C)C)N.Cl

Synonyms (18)
  • H-Glu(OtBu)-OtBu.HCl
  • L-Glu(OtBu)-OtBu.HCl