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Home/Compounds/Pharmaceutical Intermediate/DMTr-TNA-5MeU amidite
C39H47N4O8P
730.8 g/mol
Pharmaceutical Intermediate

DMTr-TNA-5MeU amidite

CAS325683-94-1
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate

DMTr-TNA-5MeU amidite is a nucleoside phosphoramidite used as a building block in oligonucleotide synthesis. It features a protected thymine analog and a phosphoramidite group, enabling automated solid-phase assembly of modified DNA or RNA sequences.

Reagent for oligonucleotide synthesisBuilding block for modified nucleic acid research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

3-[[(2R,3R,4S)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-2-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChIKey

CEPXSVFEFKTSLF-MVFNBKNKSA-N

SMILES

CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@H](CO2)OC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N(C(C)C)C(C)C)OCCC#N

Synonyms (5)
  • DMTr-TNA-5MeU amidite