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Home/Compounds/Pharmaceutical Intermediate/N-(3,4-Dichlorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
C14H7Cl2FN4O2
353.1 g/mol
Pharmaceutical Intermediate

N-(3,4-Dichlorophenyl)-7-fluoro-6-nitroquinazolin-4-amine

CAS2512206-82-3EC942-240-7
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate

This compound is a nitro-substituted quinazoline derivative used as an impurity reference standard in the quality control manufacturing of afatinib. It is primarily supplied to pharmaceutical and research laboratories for analytical method development and batch release testing.

impurity reference standard for afatinibanalytical standard for pharmaceutical quality control

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 2512206-82-3

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Related Compounds

StrongStructure SimilarSimilarity 0.87

N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine

CAS162012-67-1

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StrongStructure SimilarSimilarity 0.87

N-(4-Chloro-3-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine

CAS2475095-50-0

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.77

N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine

CAS2226537-61-5

pharmaceutical intermediate

ReferenceSame Category

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pharmaceutical intermediate

ReferenceSame Category

3-Amino-4-(2-fluorophenyl)-1-methyl-6-nitroquinolin-2(1H)-one

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pharmaceutical intermediate

ReferenceSame Category

1-Hydroxymethyl-3-cyclopentene

CAS25125-21-7

pharmaceutical intermediate

ReferenceSame Category

Ethyl (3R)-piperidine-3-carboxylate

CAS25137-01-3

pharmaceutical intermediate

Referencesame scaffold

4-((3-Chloro-4-fluorophenyl)amino)-6-nitroquinazolin-7-ol

CAS1449430-45-8

pharmaceutical intermediate

Identifiers
IUPAC Name

N-(3,4-dichlorophenyl)-7-fluoro-6-nitroquinazolin-4-amine

InChIKey

BZUFBRLIMSOXIS-UHFFFAOYSA-N

SMILES

C1=CC(=C(C=C1NC2=NC=NC3=CC(=C(C=C32)[N+](=O)[O-])F)Cl)Cl

Synonyms (3)
  • Afatinib Impurity 133