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Home/Compounds/Pharmaceutical Intermediate/N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
C14H7F3N4O2
320.23 g/mol
Pharmaceutical Intermediate

N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine

CAS2226537-61-5EC942-239-1
Category
Pharmaceutical Intermediate
Compound Class
Aromatic
Primary Use
Pharmaceutical Intermediate

This compound is a fluorinated nitroquinazoline derivative used as a pharmaceutical intermediate in the manufacturing of afatinib impurities. Its structure features multiple halogen and amine functional groups, contributing to its role in research and development.

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 2226537-61-5

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Related Compounds

SimilarStructure SimilarSimilarity 0.81

N-(4-Chloro-3-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine

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SimilarStructure SimilarSimilarity 0.81

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SimilarStructure SimilarSimilarity 0.77

N-(3,4-Dichlorophenyl)-7-fluoro-6-nitroquinazolin-4-amine

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pharmaceutical intermediate

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(R)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine

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ReferenceSame Category

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ReferenceSame Category

(R)-7,8-Difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-ol

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pharmaceutical intermediate

Identifiers
IUPAC Name

N-(3,4-difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine

InChIKey

DZRYHCITHKPDFS-UHFFFAOYSA-N

SMILES

C1=CC(=C(C=C1NC2=NC=NC3=CC(=C(C=C32)[N+](=O)[O-])F)F)F

Synonyms (2)

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