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Home/Compounds/API/Belotecan hydrochloride
C25H28ClN3O4
470 g/mol
API

Belotecan hydrochloride

CAS213819-48-8
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Belotecan hydrochloride is the hydrochloride salt of the semi-synthetic camptothecin analogue belotecan. It functions as a topoisomerase I inhibitor, stabilizing the cleavable complex of topoisomerase I-DNA and disrupting DNA replication, which is relevant to its role in pharmaceutical research and manufacturing.

pharmaceutical raw material for anticancer compound manufacturingresearch compound for topoisomerase I inhibition studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

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Referencesame scaffold

7-ethyl-10-hydroxycamptothecin

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Gimatecan

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Referencesame scaffold

Camptothecin

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Identifiers
IUPAC Name

(19S)-19-ethyl-19-hydroxy-10-[2-(propan-2-ylamino)ethyl]-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione;hydrochloride

InChIKey

SJKBXKKZBKCHET-UQIIZPHYSA-N

SMILES

CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C5=CC=CC=C5N=C4C3=C2)CCNC(C)C)O.Cl

Synonyms (13)
  • Belotecan hydrochloride (USAN)
  • Belotecan HCl
  • Belotecan hydrochloride
  • CKD-602 hydrochloride
  • CKD602 HCl
  • Camtobell hydrochloride