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Home/Compounds/API/Händel-Werke-Verzeichnis
C28H30FN3O4
491.6 g/mol
API

ABBV 744

CAS2138861-99-9
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

ABBV 744 is an orally bioavailable inhibitor of the Bromodomain and Extra-Terminal (BET) family of proteins, preferentially targeting the second bromodomain (BD2). It is used as an active pharmaceutical ingredient in research focused on disrupting BET protein interactions with acetylated histones, thereby modulating gene expression and cell proliferation.

Pharmaceutical raw material for BET inhibitor researchLaboratory reagent for BD2-selective inhibition studiesCompound for epigenetic target investigation

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

N-ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide

InChIKey

OEDSFMUSNZDJFD-UHFFFAOYSA-N

SMILES

CCNC(=O)C1=CC2=C(N1)C(=O)N(C=C2C3=C(C=CC(=C3)C(C)(C)O)OC4=C(C=C(C=C4C)F)C)C

Synonyms (10)
  • HWV
  • ABBV 744
  • US10633379, Example 35
  • US10633379, Example 82