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Home/Compounds/Research Reagent/Methyl 5-(butan-2-yl)-14-(fluoroacetyl)-11-(1-hydroxyethyl)-8-(3-methoxy-3-oxopropyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate (non-preferred name)
C30H43FN4O11
654.7 g/mol
Research Reagent

Z-IETD-fmk

CAS210344-98-2
Category
Research Reagent
Compound Class
Peptide
Primary Use
Research Compound

Z-IETD-fmk is a research reagent commonly employed as a caspase-8 inhibitor in laboratory studies. This fluoromethyl ketone peptide analog is designed for investigating apoptosis pathways.

caspase-8 inhibition researchapoptosis pathway studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 210344-98-2

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Identifiers
IUPAC Name

methyl (4S)-5-[[(2S,3R)-1-[[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-4-[[(2S,3S)-3-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-5-oxopentanoate

InChIKey

PHLCQASLWHYEMX-DEKIMQJDSA-N

SMILES

CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)OC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)OCC1=CC=CC=C1

Synonyms (11)
  • Caspase-8 Inhibitor II
  • Z-IE(OMe)TD(OMe)-FMK
  • Z-IETD-fmk
  • caspase-8 inhibitor