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Home/Compounds/Research Reagent/1-(2'-O,4-C-Methylene-beta-D-ribofuranosyl)thymine
C11H14N2O6
270.24 g/mol
Research ReagentWarning

1-((1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

CAS206055-67-6
Category
Research Reagent
Compound Class
Heterocycle
Primary Use
Research Compound

This compound is a locked nucleic acid (LNA) research reagent featuring a bicyclic furanose ring system with a 5-methylpyrimidine base. It is primarily used in nucleic acid chemistry for the synthesis of modified oligonucleotides with enhanced binding affinity and stability.

Locked nucleic acid researchSynthesis of modified oligonucleotides

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 206055-67-6

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Referencesame scaffold

1-(2'-O,4-C-Methylene-beta-D-ribofuranosyl)uridine

CAS200435-92-3

pharmaceutical intermediate

Safety Reference

Harmful
Harmful
Warning
H302Harmful if swallowed
Identifiers
IUPAC Name

1-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-5-methylpyrimidine-2,4-dione

InChIKey

TYYUAZVXLRMUMN-SZVQBCOZSA-N

SMILES

CC1=CN(C(=O)NC1=O)[C@H]2[C@H]3[C@@H]([C@@](O2)(CO3)CO)O

Synonyms (14)
  • 2'-O, 4'-C-METHYLENETHYMINE
  • LNA-T diol
  • Locked Nucleic Acid Thymidine