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Home/Compounds/API/Pexidartinib hydrochloride
C20H16Cl2F3N5
454.3 g/mol
API

Pexidartinib hydrochloride

CAS2040295-03-0
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

Pexidartinib hydrochloride is the hydrochloride salt form of pexidartinib, a small-molecule receptor tyrosine kinase inhibitor that targets KIT, CSF1R, and FLT3. It is primarily used as an active pharmaceutical ingredient in research and pharmaceutical manufacturing, with antineoplastic activity studied in cancer cell lines.

active pharmaceutical ingredient for research and manufacturingresearch compound for kinase inhibition studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Referencesame scaffold

6-Fluoro-N-((5-fluoro-2-methoxypyridin-3-yl)methyl)-5-((5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)pyridin-2-amine

CAS1303420-67-8

research compound

Identifiers
IUPAC Name

5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyridin-2-amine;hydrochloride

InChIKey

CJLUYLRKLUYCEK-UHFFFAOYSA-N

SMILES

C1=CC(=NC=C1CC2=CNC3=C2C=C(C=N3)Cl)NCC4=CN=C(C=C4)C(F)(F)F.Cl

Synonyms (15)
  • Pexidartinib hydrochloride (JAN/USAN)
  • 2040295-03-0 (HCl)
  • PLX3397 HCl
  • PLX3397 HYDROCHLORIDE
  • Pexidartinib HCl
  • Pexidartinib hydrochloride
  • Turalio (TN)