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Home/Compounds/Research Reagent/6-Fluoro-N-((5-fluoro-2-methoxypyridin-3-yl)methyl)-5-((5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)pyridin-2-amine
C21H19F2N5O
395.4 g/mol
Research Reagent

6-Fluoro-N-((5-fluoro-2-methoxypyridin-3-yl)methyl)-5-((5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)pyridin-2-amine

CAS1303420-67-8
Category
Research Reagent
Compound Class
Heterocycle
Primary Use
Research Compound

PLX5622 is a highly selective, brain-penetrant, orally active inhibitor of colony-stimulating factor 1 receptor (CSF1R), used in research to enable prolonged and specific elimination of microglial cells. It is primarily administered via a feed-free diet and exhibits favorable pharmacokinetic properties in various animal models.

Research tool for microglial cell eliminationCompound for studying CSF1R inhibition in vivoLaboratory reagent for pharmacokinetic studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

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NONANOIC-D17 ACID

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Referencesame scaffold

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pharmaceutical raw material

Customs Tariff Classification

The international HS code for 6-Fluoro-N-((5-fluoro-2-methoxypyridin-3-yl)methyl)-5-((5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)pyridin-2-amine (CAS 1303420-67-8) is 2933.39.

HS code (international, 6-digit)

2933.39

EU CN code (8-digit)

2933 39 99

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

6-fluoro-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine

InChIKey

NSMOZFXKTHCPTQ-UHFFFAOYSA-N

SMILES

CC1=CC2=C(NC=C2CC3=C(N=C(C=C3)NCC4=C(N=CC(=C4)F)OC)F)N=C1

Synonyms (9)
  • PLX 5622
  • PLX5622 free base
  • US9096593, P-2049

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