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Home/Compounds/Pharmaceutical Intermediate/N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-L-ornithine
C19H30N4O5S
426.5 g/mol
Pharmaceutical Intermediate

N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-L-ornithine

CAS200115-86-2
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

This compound is a protected arginine derivative used as a building block in peptide synthesis. It features a sulfonyl-protecting group on the guanidino side chain, enabling controlled stepwise assembly of arginine-containing peptides in laboratory research and pharmaceutical manufacturing.

Building block for solid-phase peptide synthesisReagent for the preparation of arginine-containing peptides

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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N-Boc-N'-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sufonyl)-L-arginine

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N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(1,1-dimethylethoxy)carbonyl]-D-ornithine

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Related Reading

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2026 has been a concentrated year for peptide therapeutics. Efficacy reached a new high in late-stage trials, the obesity field moved beyond the incretins to amylin, the oral route reached weight management, and peptide-guided radioligand therapy kept advancing — each point tied to a specific 2025–2026 result.

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Identifiers
IUPAC Name

(2S)-2-amino-5-[[amino-[(2,2,4,6,7-pentamethyl-3H-1-benzofuran-5-yl)sulfonylamino]methylidene]amino]pentanoic acid

InChIKey

GVIXTVCDNCXXSH-AWEZNQCLSA-N

SMILES

CC1=C(C(=C(C2=C1OC(C2)(C)C)C)S(=O)(=O)NC(=NCCC[C@@H](C(=O)O)N)N)C

Synonyms (12)
  • Arg(Pbf)
  • H-Arg(Pbf)-OH.nH2O
  • h-arg(pbf)-oh

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