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Home/Compounds/Pharmaceutical Intermediate/N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methylcytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
C42H52N5O9P
801.9 g/mol
Pharmaceutical Intermediate

Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

CAS199593-09-4
Category
Pharmaceutical Intermediate
Compound Class
Amide
Primary Use
Pharmaceutical Intermediate

This compound is a phosphoramidite monomer used as a building block in oligonucleotide synthesis. It features a complex structure with multiple aromatic rings, ether linkages, and a phosphoramidite group, making it suitable for solid-phase DNA/RNA assembly.

Solid-phase oligonucleotide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 199593-09-4

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Related Compounds

StrongStructure SimilarSimilarity 0.90

N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-2'-O-methylcytidine

CAS110764-78-8

Oligonucleotide synthesis building block

StrongStructure SimilarSimilarity 0.88

N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]cytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

CAS121058-88-6

pharmaceutical intermediate

StrongStructure SimilarSimilarity 0.88

N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-deoxy-2'-fluorocytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

CAS159414-99-0

pharmaceutical intermediate

StrongStructure SimilarSimilarity 0.87

(2R,3R,4R,5R)-5-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

CAS1498305-51-3

pharmaceutical intermediate

ReferenceSame Category

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CAS1996-29-8

pharmaceutical intermediate

ReferenceSame Category

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CAS199657-47-1

pharmaceutical intermediate

ReferenceSame Category

N-Fmoc-4-Cyclopropyl-L-phenylalanine

CAS1997389-26-0

pharmaceutical intermediate

ReferenceSame Category

HCV-IN-31

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pharmaceutical intermediate

Identifiers
IUPAC Name

N-[1-[(2R,3S,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

InChIKey

WNWUMIPFLOKTEZ-MNVCMFJRSA-N

SMILES

CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@H]1OC)N2C=CC(=NC2=O)NC(=O)C)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

Synonyms (13)
  • 2'-OMe-Ac-CPhosphoramidite