C22H22N2O4
378.4 g/mol
APIDanger
Ambrisentan
CAS177036-94-1EC658-059-9
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Ambrisentan is a diarylmethane compound that functions as an endothelin receptor antagonist. It is supplied as a pharmaceutical raw material for use in the manufacturing of finished dosage forms.
pharmaceutical raw material for endothelin receptor antagonist formulationsactive pharmaceutical ingredient for pulmonary arterial hypertension therapy
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
SimilarStructure SimilarSimilarity 0.81
Methyl (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoate
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pharmaceutical raw material
ReferenceSame Category
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pharmaceutical raw material
ReferenceSame Category
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ReferenceSame Category
Revaprazan hydrochloride
CAS178307-42-1
pharmaceutical raw material
Referencestereoisomer of
(+/-)-ambrisentan
CAS713516-99-5
pharmaceutical raw material
Referencestereoisomer of
(R)-ambrisentan
CAS1007358-76-0
pharmaceutical raw material
Safety Reference
Danger
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
Customs Tariff Classification
The international HS code for Ambrisentan (CAS 177036-94-1) is 2933.59.
HS code (international, 6-digit)
2933.59
EU CN code (8-digit)
2933 59 95
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
(2S)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid
InChIKey
OUJTZYPIHDYQMC-LJQANCHMSA-N
SMILES
CC1=CC(=NC(=N1)O[C@H](C(=O)O)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC)C
Synonyms (21)
- Ambrisentan (JAN/INN)
- (S)-ambrisentan
- AMBRISENTAN [MART.]
- Ambrisentan
- Ambrisentan (Standard)
- BSF 208075;LU 208075
- GSK 1325760A
- Letairis
- Letairis (TN)
- Pulmonext
- Volibris
- Volibris (TN)
- ambrisentanum
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