C27H29N5O6S
551.6 g/mol
APIDanger
Bosentan
CAS147536-97-8
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Bosentan is a dual endothelin receptor antagonist used as an active pharmaceutical ingredient in the manufacturing of medications for pulmonary arterial hypertension.
active pharmaceutical ingredient for pulmonary arterial hypertension therapiesresearch compound for endothelin receptor studies
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 147536-97-8
Related Compounds
StrongSame Parent
Bosentan hydrate
CAS157212-55-0
pharmaceutical raw material
StrongSame Parent
4-(tert-Butyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide hydrochloride
CAS1196074-08-4
pharmaceutical raw material
SimilarStructure SimilarSimilarity 0.72
4-tert-Butyl-N-(6-chloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide
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pharmaceutical intermediate
ApplicationSame Use
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ReferenceSame Category
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Safety Reference
Danger
H302Harmful if swallowed
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H412Harmful to aquatic life with long lasting effects
Identifiers
IUPAC Name
4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
InChIKey
GJPICJJJRGTNOD-UHFFFAOYSA-N
SMILES
CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC
Synonyms (27)
- K86
- Bosentan (INN)
- 147536-97-8 (free)
- Actelion
- Anhydrous bosentan
- Bosentan
- Bosentan (Standard)
- Bosentan (as monohydrate)
- Bosentan - Bio-X trade mark
- Ro 47-0203
- Ro 47-0203/029
- Ro 47-0203/039
- Tracleer
- bosentan anhydrous
- bosentanum