C64H110N6O16
1219.6 g/mol
APIDanger
Aliskiren hemifumarate
CAS173334-58-2
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material
Aliskiren hemifumarate is the hemifumarate salt of aliskiren, a direct renin inhibitor used as an active pharmaceutical ingredient. It is primarily significant as an antihypertensive agent in pharmaceutical manufacturing.
antihypertensive agentactive pharmaceutical ingredient in cardiovascular medications
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
StrongSame Parent
(2S,4S,5S,7S)-7-(3-(3-Methoxypropoxy)-4-methoxybenzyl)-5-amino-N-(2-carbamoyl-2-methylpropyl)-4-hydroxy-2-isopropyl-8-methylnonanamide hydrochloride
CAS173399-03-6
pharmaceutical raw material
StrongSame Parent
Aliskiren
CAS173334-57-1
pharmaceutical raw material
ReferenceSame Category
Lamivudine salicylate
CAS173522-96-8
pharmaceutical raw material
ReferenceSame Category
4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene
CAS174264-46-1
pharmaceutical raw material
ReferenceSame Category
6-tert-Butyldimethylsilyl-4'-hydroxy Raloxifene
CAS174264-47-2
pharmaceutical raw material
ReferenceSame Category
Raloxifene 6-glucuronide
CAS174264-50-7
pharmaceutical raw material
Referencestereoisomer of
Bis((2R,4R,5R,7R)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-8-methyl-2-propan-2-ylnonanamide);(E)-but-2-enedioic acid
CAS1630036-76-8
pharmaceutical intermediate
Referencestereoisomer of
(2S,4S,5S,7R)-5-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-8-methyl-2-propan-2-ylnonanamide;(E)-but-2-enedioic acid
CAS1630036-82-6
pharmaceutical intermediate for research
Safety Reference
Danger
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
Identifiers
IUPAC Name
bis((2S,4S,5S,7S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-8-methyl-2-propan-2-ylnonanamide);(E)-but-2-enedioic acid
InChIKey
KLRSDBSKUSSCGU-KRQUFFFQSA-N
SMILES
CC(C)[C@@H](CC1=CC(=C(C=C1)OC)OCCCOC)C[C@@H]([C@H](C[C@@H](C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N.CC(C)[C@@H](CC1=CC(=C(C=C1)OC)OCCCOC)C[C@@H]([C@H](C[C@@H](C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N.C(=C/C(=O)O)\C(=O)O
Synonyms (30)
- Aliskiren fumarate (JAN/USAN)
- ALISKIREN (AS FUMARATE)
- ALISKIREN FUMARATE [MART.]
- Aliskiren fumarate
- Aliskiren hemifumarate
- Enviage
- Rasilez
- Riprazo
- Sprimeo
- Tekturna
- Tekturna (TN)
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