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Home/Compounds/Pharmaceutical Intermediate/Bis((2R,4R,5R,7R)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-8-methyl-2-propan-2-ylnonanamide);(E)-but-2-enedioic acid
C64H110N6O16
1219.6 g/mol
Pharmaceutical Intermediate

Bis((2R,4R,5R,7R)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-8-methyl-2-propan-2-ylnonanamide);(E)-but-2-enedioic acid

CAS1630036-76-8
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

This compound is the hemifumarate salt of aliskiren, a pharmaceutical intermediate used in research and manufacturing processes. It is a multi-component, salt-like substance with complex stereochemistry and a large, flexible molecular structure.

pharmaceutical intermediate in aliskiren manufacturingresearch compound for analytical or synthetic studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

(3S,4R)-4-aminooxan-3-ol hydrochloride

CAS1630815-44-9

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ReferenceSame Category

(3R,4S)-3-Fluorotetrahydro-2H-pyran-4-amine hydrochloride

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pharmaceutical intermediate

ReferenceSame Category

Tert-butyl N-[(3R,4S)-3-fluoropiperidin-4-yl]carbamate

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ReferenceSame Category

6-Chloro-9-(2,3,5-tri-O-acetylpentofuranosyl)-1,9-dihydro-2H-purin-2-imine

CAS16321-99-6

pharmaceutical intermediate

Referencestereoisomer of

(2S,4S,5S,7R)-5-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-8-methyl-2-propan-2-ylnonanamide;(E)-but-2-enedioic acid

CAS1630036-82-6

pharmaceutical intermediate for research

Referencestereoisomer of

Aliskiren

CAS173334-57-1

pharmaceutical raw material

Referencestereoisomer of

Aliskiren hemifumarate

CAS173334-58-2

pharmaceutical raw material

Referencestereoisomer of

(2S,4S,5S,7S)-7-(3-(3-Methoxypropoxy)-4-methoxybenzyl)-5-amino-N-(2-carbamoyl-2-methylpropyl)-4-hydroxy-2-isopropyl-8-methylnonanamide hydrochloride

CAS173399-03-6

pharmaceutical raw material

Related Reading

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2026 has been a concentrated year for peptide therapeutics. Efficacy reached a new high in late-stage trials, the obesity field moved beyond the incretins to amylin, the oral route reached weight management, and peptide-guided radioligand therapy kept advancing — each point tied to a specific 2025–2026 result.

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Identifiers
IUPAC Name

bis((2R,4R,5R,7R)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-8-methyl-2-propan-2-ylnonanamide);(E)-but-2-enedioic acid

InChIKey

KLRSDBSKUSSCGU-CTOTZSFUSA-N

SMILES

CC(C)[C@H](CC1=CC(=C(C=C1)OC)OCCCOC)C[C@H]([C@@H](C[C@H](C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N.CC(C)[C@H](CC1=CC(=C(C=C1)OC)OCCCOC)C[C@H]([C@@H](C[C@H](C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N.C(=C/C(=O)O)\C(=O)O

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