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Home/Compounds/Pharmaceutical Intermediate/2'-O-(2-Methoxyethyl)-5-methyluridine
C13H20N2O7
316.31 g/mol
Pharmaceutical Intermediate

2'-O-(2-Methoxyethyl)-5-methyl-uridine

CAS163759-49-7
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a modified nucleoside, O2'-(2-methoxyethyl)-5-methyl-uridine, used as a building block in oligonucleotide synthesis. It features a methoxyethyl modification at the 2'-oxygen position of the ribose sugar, which enhances stability and properties of synthetic RNA molecules.

pharmaceutical intermediate for oligonucleotide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ApplicationSame Use

(S)-DMT-glycidol-T

CAS168332-12-5

pharmaceutical intermediate

ReferenceSame Category

5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyluridine

CAS163759-50-0

pharmaceutical intermediate

ReferenceSame Category

N-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-((2-cyanoethoxy)(diisopropylamino)phosphino)-2'-O-(2-methoxyethyl)-5-methylcytidine

CAS163759-94-2

pharmaceutical intermediate

ReferenceSame Category

5'-O-DMT-2'-(2-methoxyethyl)uridine 3'-CE phosphoramidite

CAS163759-97-5

pharmaceutical intermediate

ReferenceSame Category

(R)-4-Boc-2-methylpiperazine

CAS163765-44-4

pharmaceutical intermediate

Identifiers
IUPAC Name

1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

InChIKey

NEVQCHBUJFYGQO-DNRKLUKYSA-N

SMILES

CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)OCCOC

Synonyms (11)
  • 2'-MOE-5-Methyluridine
  • 2'-O-MOE-5-Me-rU
  • 2'-O-Methoxyethyl-thymidine