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Home/Compounds/Pharmaceutical Intermediate/Fmoc-D-Trp(Boc)-OH
C31H30N2O6
526.6 g/mol
Pharmaceutical Intermediate

1-(tert-Butoxycarbonyl)-N-(((9H-fluoren-9-yl)methoxy)carbonyl)-D-tryptophan

CAS163619-04-3
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

This compound is a protected amino acid derivative used in peptide synthesis. It features a fluorenylmethoxycarbonyl (Fmoc) protecting group on the amino terminus and a tert-butoxycarbonyl (Boc) group on the indole nitrogen, enabling selective deprotection during solid-phase peptide assembly.

Protected building block for solid-phase peptide synthesisResearch reagent for preparing tryptophan-containing peptides

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.76

Fmoc-Trp(N-CH2-COOtBu)-OH

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research compound

SimilarStructure SimilarSimilarity 0.73

N-Boc-N'-Boc-L-tryptophan

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SimilarStructure SimilarSimilarity 0.73

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-methyl-L-tryptophan

CAS1334509-86-2

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ReferenceSame Category

(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(2-methylsulfanylethylamino)-2-(3,3,3-trifluoropropylsulfanyl)purin-9-yl]oxolane-3,4-diol

CAS163706-58-9

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ReferenceSame Category

Tributylamine (dichloromethylene)bis(phosphonate)

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ReferenceSame Category

Afatinib Impurity I

CAS1637254-93-3

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ReferenceSame Category

2'-Deoxyadenosine monohydrate

CAS16373-93-6

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Referencestereoisomer of

Fmoc-Trp(Boc)-OH

CAS143824-78-6

pharmaceutical intermediate

Related Reading

Therapeutic Peptides in 2026: This Year's Breakthroughs

2026 has been a concentrated year for peptide therapeutics. Efficacy reached a new high in late-stage trials, the obesity field moved beyond the incretins to amylin, the oral route reached weight management, and peptide-guided radioligand therapy kept advancing — each point tied to a specific 2025–2026 result.

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Customs Tariff Classification

The international HS code for 1-(tert-Butoxycarbonyl)-N-(((9H-fluoren-9-yl)methoxy)carbonyl)-D-tryptophan (CAS 163619-04-3) is 2933.99.

HS code (international, 6-digit)

2933.99

EU CN code (8-digit)

2933 99 80

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid

InChIKey

ADOHASQZJSJZBT-AREMUKBSSA-N

SMILES

CC(C)(C)OC(=O)N1C=C(C2=CC=CC=C21)C[C@H](C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35

Synonyms (15)
  • 1-Boc-Fmoc-D-tryptophan
  • 1-Boc-N-Fmoc-D-tryptophan
  • Fmoc-D-Trp(Boc)-OH

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