Home/Compounds/Pharmaceutical Intermediate/N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-methyl-L-tryptophan
C27H24N2O4
440.5 g/mol
Pharmaceutical IntermediateWarning
(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(1-methyl-1H-indol-3-yl)propanoic acid
CAS1334509-86-2EC962-103-5
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate
This compound is a protected amino acid derivative used as a building block in solid-phase peptide synthesis. It features a fluorenylmethoxycarbonyl (Fmoc) protecting group on the amine and a methylated indole side chain, making it suitable for incorporating modified tryptophan residues into peptides.
Building block for Fmoc-based solid-phase peptide synthesisIntroduction of N1-methyltryptophan into peptide chains
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 1334509-86-2
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Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-methylindol-3-yl)propanoic acid
InChIKey
GDPXIUSEXJJUGT-DEOSSOPVSA-N
SMILES
CN1C=C(C2=CC=CC=C21)C[C@@H](C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35
Synonyms (8)
- FMOC-TRP(ME)-OH
- Fmoc-Trp(1-Me)-OH
- N-Fmoc-1-methyl-L-tryptophan