This compound is a pharmaceutical intermediate specifically used in the synthesis of eribulin, a complex macrocyclic ether known for its anticancer activity. It features a tetrahydrofuran ring with an attached iodinated alkene side chain and a pivalate ester group.
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 157322-47-9
Eribulin mesylate intermediate
pharmaceutical intermediate
1-BOC-3-[(DIMETHYLAMINO)METHYLENE]-4-OXOPIPERIDINE
pharmaceutical intermediate
2'-dG(iBu)-2'-phosphoramidite
pharmaceutical intermediate
5-Chlorovaleryl chloride
pharmaceutical intermediate
3-((2S,5S)-5-(3-hydroxypropyl)-4-methylenetetrahydrofuran-2-yl)propyl pivalate
pharmaceutical intermediate
3-((2S,5S)-5-((3R,5R)-5-Methyl-3-((methylsulfonyl)oxy)-6-(((trifluoromethyl)sulfonyl)oxy)hept-6-en-1-yl)-4-methylenetetrahydrofuran-2-yl)propyl pivalate
pharmaceutical intermediate
3-[5-(3-hydroxy-6-iodo-5-methylhept-6-enyl)-4-methylideneoxolan-2-yl]propyl 2,2-dimethylpropanoate
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