This compound is a highly functionalized polycyclic ether intermediate used in the synthesis of eribulin mesylate, a pharmaceutical agent. Its structure features multiple silyl-protected hydroxyl groups and an iodine-substituted alkene moiety, reflecting its role as a building block in complex organic synthesis.
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Sourcing Eribulin mesylate intermediate?
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Methyl 2-((2R,4aS,6S,7R,8S,8aS)-7,8-bis((tert-butyldimethylsilyl)oxy)-6-((S,E)-1-((tert-butyldimethylsilyl)oxy)-3-(trimethylsilyl)allyl)octahydropyrano[3,2-b]pyran-2-yl)acetate
pharmaceutical intermediate
1-BOC-3-[(DIMETHYLAMINO)METHYLENE]-4-OXOPIPERIDINE
pharmaceutical intermediate
2'-dG(iBu)-2'-phosphoramidite
pharmaceutical intermediate
5-Chlorovaleryl chloride
pharmaceutical intermediate
N-(tert-Butoxycarbonyl)-L-alanine
pharmaceutical intermediate
methyl 2-[(2S,3R,4S,4aS,6R,8aS)-3,4-bis[[tert-butyl(dimethyl)silyl]oxy]-2-[(E,1S)-1-[tert-butyl(dimethyl)silyl]oxy-3-iodoprop-2-enyl]-2,3,4,4a,6,7,8,8a-octahydropyrano[3,2-b]pyran-6-yl]acetate
MIEJSEPCTMXSCI-SUCSLEJPSA-N
CC(C)(C)[Si](C)(C)O[C@H]1[C@@H]2[C@H](CC[C@@H](O2)CC(=O)OC)O[C@H]([C@H]1O[Si](C)(C)C(C)(C)C)[C@H](/C=C/I)O[Si](C)(C)C(C)(C)C
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Sourcing Eribulin mesylate intermediate?
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