ChemAbout
© 2026 ChemAbout
Insights|Privacy Policy|Terms of Service|[email protected]
Home/Compounds/Pharmaceutical Intermediate/(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester
C21H21F2N3O4S
449.5 g/mol
Pharmaceutical Intermediate

2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol

CAS149809-43-8
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a chiral sulfonate ester used as a pharmaceutical intermediate in the synthesis of antifungal agents. Its structure features a difluorophenyl-substituted tetrahydrofuran core linked to a triazole ring, with a tosylate leaving group.

Pharmaceutical intermediate for antifungal synthesisResearch compound in medicinal chemistry

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

Sourcing or supplying this compound?

List your inventory or post a purchase request

CAS 149809-43-8

List This Product
Sign in to publish supply information
Request This Product
Submit a request without registering

Related Compounds

SimilarStructure SimilarSimilarity 0.85

(3S-cis)-4-Chlorobenzenesulfonic acid [5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)-3-furanyl]methyl ester

CAS175712-02-4

pharmaceutical intermediate

ApplicationSame Use

2',4'-dichloroacetophenone

CAS2234-16-4

pharmaceutical intermediate

ReferenceSame Category

Methyl-N-tert-butyloxycarbonyl-amino-4,4'-biphenyl-R-alanine

CAS149818-98-4

pharmaceutical intermediate

ReferenceSame Category

(2R,3R,4R,5R)-5-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

CAS1498305-51-3

pharmaceutical intermediate

ReferenceSame Category

Tert-butyl 5-aminothiophene-2-carboxylate

CAS1498311-57-1

pharmaceutical intermediate

ReferenceSame Category

(6S)-6-[5-[7-[2-(1R,3S,4S)-2-Azabicyclo[2.2.1]hept-3-yl-1H-benzimidazol-6-yl]-9,9-difluoro-9H-fluoren-2-yl]-1H-imidazol-2-yl]-5-azaspiro[2.4]heptane hydrochloride (1:4)

CAS1499193-67-7

pharmaceutical intermediate

Identifiers
IUPAC Name

[(3S,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methyl 4-methylbenzenesulfonate

InChIKey

DFWVLCJRFGIRAK-KKSFZXQISA-N

SMILES

CC1=CC=C(C=C1)S(=O)(=O)OC[C@H]2C[C@](OC2)(CN3C=NC=N3)C4=C(C=C(C=C4)F)F

Synonyms (20)
  • Posaconazole Impurity 10
  • Posaconazole primary ring