C24H28NNaO5
433.5 g/mol
APIWarning
Sacubitril sodium
CAS149690-05-1
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material
Sacubitril sodium is an active pharmaceutical ingredient that functions as a neprilysin inhibitor. It is a key component in the combination medication sacubitril/valsartan, which is used in the management of heart failure.
Pharmaceutical raw material for combination therapyComponent in angiotensin receptor-neprilysin inhibitor (ARNi) formulations
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 149690-05-1
Related Compounds
StrongSame Parent
Sacubitril calcium
CAS1369773-39-6
pharmaceutical raw material
ReferenceSame Category
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ReferenceSame Category
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ReferenceSame Category
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ReferenceSame Category
9-Amino-minocycline hydrochloride
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pharmaceutical raw material
Referencestereoisomer of
Sacubitril
CAS149709-62-6
pharmaceutical raw material
Referencestereoisomer of
Alpha-Ethyl (alphaS,gammaS)-gamma-((3-carboxy-1-oxopropyl)amino)-alpha-methyl(1,1'-biphenyl)-4-pentanoate
CAS149709-63-7
pharmaceutical raw material
Referencestereoisomer of
2R,4R-Sacubitril
CAS766480-48-2
pharmaceutical raw material
Safety Reference
Warning
H302Harmful if swallowed
H312Harmful in contact with skin
H319Causes serious eye irritation
H332Harmful if inhaled
H361Suspected of damaging fertility or the unborn child
H413May cause long lasting harmful effects to aquatic life
Identifiers
IUPAC Name
sodium 4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate
InChIKey
RRTBVEJIZWGATF-JKSHRDEXSA-M
SMILES
CCOC(=O)[C@H](C)C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)[O-].[Na+]
Synonyms (7)
- AHU-377 sodium salt
- Ahu-377 sodium
- Sacubitril Sodium Salt
- Sacubitril sodium