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Home/Compounds/API/Ahu-377 sodium
C24H28NNaO5
433.5 g/mol
APIWarning

Sacubitril sodium

CAS149690-05-1
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material

Sacubitril sodium is an active pharmaceutical ingredient that functions as a neprilysin inhibitor. It is a key component in the combination medication sacubitril/valsartan, which is used in the management of heart failure.

Pharmaceutical raw material for combination therapyComponent in angiotensin receptor-neprilysin inhibitor (ARNi) formulations

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Sacubitril calcium

CAS1369773-39-6

pharmaceutical raw material

ReferenceSame Category

Clemastine fumarate

CAS14976-57-9

pharmaceutical raw material

ReferenceSame Category

Cloperastine hydrochloride

CAS14984-68-0

pharmaceutical raw material

ReferenceSame Category

Sodium dibunate

CAS14992-59-7

pharmaceutical raw material

ReferenceSame Category

9-Amino-minocycline hydrochloride

CAS149934-21-4

pharmaceutical raw material

Referencestereoisomer of

Sacubitril

CAS149709-62-6

pharmaceutical raw material

Referencestereoisomer of

Alpha-Ethyl (alphaS,gammaS)-gamma-((3-carboxy-1-oxopropyl)amino)-alpha-methyl(1,1'-biphenyl)-4-pentanoate

CAS149709-63-7

pharmaceutical raw material

Referencestereoisomer of

2R,4R-Sacubitril

CAS766480-48-2

pharmaceutical raw material

Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Environmental Hazard
Environmental Hazard
Warning
H302Harmful if swallowed
H312Harmful in contact with skin
H319Causes serious eye irritation
H332Harmful if inhaled
H361Suspected of damaging fertility or the unborn child
H413May cause long lasting harmful effects to aquatic life

Customs Tariff Classification

The international HS code for Sacubitril sodium (CAS 149690-05-1) is 2924.29.

HS code (international, 6-digit)

2924.29

EU CN code (8-digit)

2924 29 70

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

sodium 4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate

InChIKey

RRTBVEJIZWGATF-JKSHRDEXSA-M

SMILES

CCOC(=O)[C@H](C)C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)[O-].[Na+]

Synonyms (7)
  • AHU-377 sodium salt
  • Ahu-377 sodium
  • Sacubitril Sodium Salt
  • Sacubitril sodium

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