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Home/Compounds/API/Relacorilant
C27H22F4N6O3S
586.6 g/mol
API

Relacorilant

CAS1496510-51-0
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Relacorilant is a selective glucocorticoid receptor antagonist initially investigated for hypercortisolism and later developed as a sensitizing agent in oncology. It is an active pharmaceutical ingredient used in combination with other agents for certain resistant cancers.

Active pharmaceutical ingredient for combination cancer therapySelective glucocorticoid receptor antagonist

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

[(4aR)-1-(4-fluorophenyl)-6-(1-methylpyrazol-4-yl)sulfonyl-4,5,7,8-tetrahydropyrazolo[5,4-g]isoquinolin-4a-yl]-[4-(trifluoromethyl)-2-pyridinyl]methanone

InChIKey

WANIDIGFXJFFEL-SANMLTNESA-N

SMILES

CN1C=C(C=N1)S(=O)(=O)N2CCC3=CC4=C(C[C@@]3(C2)C(=O)C5=NC=CC(=C5)C(F)(F)F)C=NN4C6=CC=C(C=C6)F

Synonyms (13)
  • Relacorilant (USAN)
  • Cort 125134
  • Lifyorli (TN)
  • Relacorilant
  • relacorilantum