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Home/Compounds/Pharmaceutical Intermediate/D-Tryptophan methyl ester hydrochloride
C12H15ClN2O2
254.71 g/mol
Pharmaceutical IntermediateDanger

Methyl (2R)-2-amino-3-(1H-indol-3-yl)propanoate hydrochloride

CAS14907-27-8EC639-469-7
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate

D-tryptophan methyl ester hydrochloride is a salt-form derivative of the amino acid D-tryptophan. It is primarily used as a pharmaceutical intermediate in the manufacturing process of tadalafil.

Pharmaceutical intermediate for tadalafil synthesisLaboratory reagent for research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Referencestereoisomer of

Methyl L-tryptophanate

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pharmaceutical intermediate

Safety Reference

Corrosive
Corrosive
Harmful
Harmful
Danger
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

methyl (2R)-2-amino-3-(1H-indol-3-yl)propanoate;hydrochloride

InChIKey

XNFNGGQRDXFYMM-HNCPQSOCSA-N

SMILES

COC(=O)[C@@H](CC1=CNC2=CC=CC=C21)N.Cl

Synonyms (23)
  • D-TRYPTOPHAN METHYL ESTER HCL
  • DTrp-OMe.HCl
  • H-D-Trp-OMe.HCl
  • Tadalafil Impurity 39
  • Tadalafil Intermediate I