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Home/Compounds/Pharmaceutical Intermediate/Ojima lactam
C22H27NO3Si
381.5 g/mol
Pharmaceutical Intermediate

(3R,4S)-1-BENZOYL-4-PHENYL-3-[(TRIETHYLSILYL)OXY]-2-AZETIDINONE

CAS149249-91-2
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a pharmaceutical intermediate used in the synthesis of the anticancer compound Taxol. This chiral beta-lactam derivative features a silyl-protected hydroxyl group and two aromatic rings.

Key intermediate for Taxol synthesisPharmaceutical manufacturing intermediate

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Referencesame scaffold

(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone

CAS201856-53-3

pharmaceutical intermediate

Identifiers
IUPAC Name

(3R,4S)-1-benzoyl-4-phenyl-3-triethylsilyloxyazetidin-2-one

InChIKey

PMFXBVOLZORTNG-VQTJNVASSA-N

SMILES

CC[Si](CC)(CC)O[C@@H]1[C@@H](N(C1=O)C(=O)C2=CC=CC=C2)C3=CC=CC=C3

Synonyms (6)

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