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Home/Compounds/API/Omaveloxolone
C33H44F2N2O3
554.7 g/mol
APIWarning

Omaveloxolone

CAS1474034-05-3
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material

Omaveloxolone is a semi-synthetic triterpenoid compound that functions as an Nrf2 activator. It is approved as a pharmaceutical raw material for use in Friedreich's ataxia in adults and adolescents aged 16 years and older.

antioxidant agentanti-inflammatory agentcardioprotective agent

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Safety Reference

Health Hazard
Health Hazard
Warning
H373May cause damage to organs through prolonged or repeated exposure
Identifiers
IUPAC Name

N-[(4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,3,4,5,6,7,8,8a,14a,14b-decahydropicen-4a-yl]-2,2-difluoropropanamide

InChIKey

RJCWBNBKOKFWNY-IDPLTSGASA-N

SMILES

C[C@@]12CC[C@]3(CCC(C[C@H]3[C@H]1C(=O)C=C4[C@]2(CC[C@@H]5[C@@]4(C=C(C(=O)C5(C)C)C#N)C)C)(C)C)NC(=O)C(C)(F)F

Synonyms (13)
  • Omaveloxolone (USAN/INN)
  • Omaveloxolone
  • RTA-408(Omaveloxolone)?
  • Skyclarys (TN)
  • omaveloxolona
  • omaveloxolonum