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Home/Compounds/Pharmaceutical Intermediate/(R)-1-Boc-3-Hydroxypiperidine
C10H19NO3
201.26 g/mol
Pharmaceutical IntermediateDanger

(R)-1-Boc-3-hydroxypiperidine

CAS143900-43-0EC626-867-0
Category
Pharmaceutical Intermediate
Compound Class
Alcohol
Primary Use
Pharmaceutical Intermediate

(R)-1-Boc-3-hydroxypiperidine is a chiral pharmaceutical intermediate featuring a protected piperidine ring with a hydroxyl substituent. It is primarily used in the synthesis of active pharmaceutical ingredients, particularly those requiring stereocontrolled building blocks.

Pharmaceutical intermediate for drug synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.81

(S)-(+)-1-Boc-3-hydroxypyrrolidine

CAS101469-92-5

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.81

(R)-1-Boc-3-hydroxypyrrolidine

CAS103057-44-9

pharmaceutical intermediate

ReferenceSame Category

(R)-4-(3-Isopropoxyphenyl)-1,3-dimethyl-1,2,3,6-tetrahydropyridine

CAS143919-32-8

pharmaceutical intermediate

ReferenceSame Category

(3R,4R)-4-(3-Isopropoxyphenyl)-1,3,4-trimethylpiperidine

CAS143919-34-0

pharmaceutical intermediate

ReferenceSame Category

4-Amino-2-chloro-5-methylpyrimidine

CAS14394-70-8

pharmaceutical intermediate

ReferenceSame Category

2-Amino-5-bromo-4-fluorobenzoic acid

CAS143945-65-7

pharmaceutical intermediate

Referencestereoisomer of

(S)-1-Boc-3-hydroxypiperidine

CAS143900-44-1

pharmaceutical intermediate

Referencestereoisomer of

1-Boc-3-hydroxypiperidine

CAS85275-45-2

pharmaceutical intermediate

Safety Reference

Corrosive
Corrosive
Toxic
Toxic
Harmful
Harmful
Danger
H301Toxic if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
Identifiers
IUPAC Name

tert-butyl (3R)-3-hydroxypiperidine-1-carboxylate

InChIKey

UIJXHKXIOCDSEB-MRVPVSSYSA-N

SMILES

CC(C)(C)OC(=O)N1CCC[C@H](C1)O

Synonyms (30)
  • (R)-1-Boc-3-hydroxypiperidine
  • (R)-1-Boc-3-piperidinol
  • Ibrutinib Impurity 58
  • N-Boc-3R-hydroxypiperidine
  • Peridine Impurity 2

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