C10H19NO3
201.26 g/mol
Pharmaceutical IntermediateWarning
Tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate
CAS143900-44-1EC626-373-5
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate
Tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate is a chemical compound used as a pharmaceutical intermediate in the manufacturing of ibrutinib, a drug substance for certain cancers. It features a piperidine ring with a hydroxyl group and a tert-butyl carbamate protecting group.
pharmaceutical intermediate for ibrutiniblaboratory reagent for organic synthesis
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 143900-44-1
Related Compounds
SimilarStructure SimilarSimilarity 0.81
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Referencestereoisomer of
1-Boc-3-hydroxypiperidine
CAS85275-45-2
pharmaceutical intermediate
Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate
InChIKey
UIJXHKXIOCDSEB-QMMMGPOBSA-N
SMILES
CC(C)(C)OC(=O)N1CCC[C@@H](C1)O
Synonyms (25)
- (S)-1-Boc-3-hydroxypiperidine
- (S)-1-Boc-3-piperidinol
- (S)-N-Boc-3-hydroxypiperidine
- Ibrutinib Interm 0441