C10H19NO3
201.26 g/mol
Pharmaceutical IntermediateWarning
Tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate
CAS143900-44-1EC626-373-5
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate
Tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate is a chemical compound used as a pharmaceutical intermediate in the manufacturing of ibrutinib, a drug substance for certain cancers. It features a piperidine ring with a hydroxyl group and a tert-butyl carbamate protecting group.
pharmaceutical intermediate for ibrutiniblaboratory reagent for organic synthesis
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
Sourcing Tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate?
Post a free purchase request — no account needed. It reaches suppliers of this product, and replies go straight to your inbox.
Related Compounds
SimilarStructure SimilarSimilarity 0.81
(S)-(+)-1-Boc-3-hydroxypyrrolidine
CAS101469-92-5
pharmaceutical intermediate
SimilarStructure SimilarSimilarity 0.81
(R)-1-Boc-3-hydroxypyrrolidine
CAS103057-44-9
pharmaceutical intermediate
SimilarStructure SimilarSimilarity 0.81
(R)-(-)-N-Boc-3-pyrrolidinol
CAS109431-87-0
pharmaceutical intermediate
ReferenceSame Category
(R)-4-(3-Isopropoxyphenyl)-1,3-dimethyl-1,2,3,6-tetrahydropyridine
CAS143919-32-8
pharmaceutical intermediate
ReferenceSame Category
(3R,4R)-4-(3-Isopropoxyphenyl)-1,3,4-trimethylpiperidine
CAS143919-34-0
pharmaceutical intermediate
ReferenceSame Category
4-Amino-2-chloro-5-methylpyrimidine
CAS14394-70-8
pharmaceutical intermediate
ReferenceSame Category
2-Amino-5-bromo-4-fluorobenzoic acid
CAS143945-65-7
pharmaceutical intermediate
Referencestereoisomer of
1-Boc-3-hydroxypiperidine
CAS85275-45-2
pharmaceutical intermediate
Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Customs Tariff Classification
The international HS code for Tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate (CAS 143900-44-1) is 2933.39.
HS code (international, 6-digit)
2933.39
EU CN code (8-digit)
2933 39 99
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate
InChIKey
UIJXHKXIOCDSEB-QMMMGPOBSA-N
SMILES
CC(C)(C)OC(=O)N1CCC[C@@H](C1)O
Synonyms (25)
- (S)-1-Boc-3-hydroxypiperidine
- (S)-1-Boc-3-piperidinol
- (S)-N-Boc-3-hydroxypiperidine
- Ibrutinib Interm 0441
Sourcing Tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate?
Post a free purchase request — no account needed. It reaches suppliers of this product, and replies go straight to your inbox.