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Home/Compounds/API/Atogepant
C29H23F6N5O3
603.5 g/mol
API

Atogepant

CAS1374248-81-3
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Atogepant is a selective oral small-molecule antagonist of the calcitonin gene-related peptide (CGRP) receptor. It is a secondary carboxamide approved for use in migraine treatment.

pharmaceutical raw materialCGRP receptor antagonist

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

(3S)-N-[(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl]-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-carboxamide

InChIKey

QIVUCLWGARAQIO-OLIXTKCUSA-N

SMILES

C[C@@H]1[C@@H](C[C@@H](C(=O)N1CC(F)(F)F)NC(=O)C2=CC3=C(C[C@@]4(C3)C5=C(NC4=O)N=CC=C5)N=C2)C6=C(C=CC(=C6F)F)F

Synonyms (16)
  • Atogepant (USAN)
  • Aquipta
  • Aquipta (TN)
  • Atogepant
  • Qulipta
  • Qulipta (TN)
  • US10272077, Example 4
  • US9833448, Example 4
  • atogepantum
  • example 4