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Home/Compounds/Pharmaceutical Intermediate/N-Cbz-Hydroxy-L-proline
C13H15NO5
265.26 g/mol
Pharmaceutical IntermediateWarning

1-(Phenylmethyl) (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate

CAS13504-85-3
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

This compound is a protected amino acid intermediate used in peptide synthesis. It features a benzyloxycarbonyl (Cbz) protecting group on the nitrogen of 4-hydroxy-L-proline, making it a key building block for the production of modified peptides and pharmaceutical intermediates.

Protected amino acid intermediate for solid-phase peptide synthesisBuilding block for the preparation of hydroxyproline-containing peptidesReagent in pharmaceutical research and manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

(2S,4R)-4-hydroxy-1-phenylmethoxycarbonylpyrrolidine-2-carboxylic acid

InChIKey

WWVCWLBEARZMAH-MNOVXSKESA-N

SMILES

C1[C@H](CN([C@@H]1C(=O)O)C(=O)OCC2=CC=CC=C2)O

Synonyms (25)
  • CBZ hydroxyproline
  • Cbz-Hyp-OH
  • N-Cbz-Hydroxy-L-proline
  • N-cbz-hydroxyproline
  • Z-Hyp-OH
  • Z-Hyp-OH, >=99.0% (T)
  • Z-L-HYP-OH