This compound is a protected guanosine derivative featuring a triisopropylsilyl (TIPS) group and a phenoxyacetyl (PAc) protecting group on the nucleobase. It is primarily used as an intermediate in the synthesis of nucleoside analogs for pharmaceutical research and manufacturing.
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 131474-72-1
5'-O-DMT-N2-DMF-dG
pharmaceutical intermediate
(S)-Ethyl 2-(2-benzyl-3-(benzyloxy)propanamido)acetate
pharmaceutical intermediate
(S)-ethyl 2-(2-benzyl-3-hydroxypropanamido)acetate
pharmaceutical intermediate
N-[(2S)-2-[[(Methylsulfonyl)oxy]methyl]-1-oxo-3-phenylpropyl]-glycine ethyl ester
pharmaceutical intermediate
Ethyl 2-((S)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetate hydrochloride
pharmaceutical intermediate
N-[9-[(6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-6-oxo-1H-purin-2-yl]-2-phenoxyacetamide
RRWDFNRJFKNJIJ-QTWDEJAXSA-N
CC(C)[Si]1(OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C3N=C(NC4=O)NC(=O)COC5=CC=CC=C5)O)O[Si](O1)(C(C)C)C(C)C)C(C)C