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Home/Compounds/Pharmaceutical Intermediate/Sodium (3R,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate
C33H34FN2NaO5
580.6 g/mol
Pharmaceutical Intermediate

(3R,5S)-Atorvastatin Sodium Salt

CAS131275-93-9
Category
Pharmaceutical Intermediate
Compound Class
Amide
Primary Use
Pharmaceutical Intermediate

This compound is the sodium salt form of a chiral atorvastatin intermediate, featuring a pyrrole core with multiple aromatic rings and hydroxyl groups. It is primarily significant as a pharmaceutical intermediate used in the manufacturing of atorvastatin.

Pharmaceutical intermediate for atorvastatin productionResearch compound in statin synthesis studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.98

Difluoro Atorvastatin Calcium Salt

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StrongStructure SimilarSimilarity 0.88

Calcium bis[(3R,5R)-7-({(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoyl}amino)-3,5-dihydroxyheptanoate]

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Referencestereoisomer of

Atorvastatin

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pharmaceutical raw material

Referencestereoisomer of

Atorvastatin calcium

CAS134523-03-8

pharmaceutical raw material

Identifiers
IUPAC Name

sodium (3R,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate

InChIKey

VVRPOCPLIUDBSA-MFHXMFJOSA-M

SMILES

CC(C)C1=C(C(=C(N1CC[C@@H](C[C@H](CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.[Na+]

Synonyms (9)
  • 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-ss,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, monosodium salt, (R*,S*)- (9CI); (3RS,5SR)-7-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid sodium salt; Atorvastatin Calcium Trihydrate Imp. B (EP) as Sodium Salt
  • (3R,5S)-Atorvastatin (sodium)