C10H17ClN2O4S3
360.9 g/mol
APIWarning
DORZOLAMIDE HYDROCHLORIDE
CAS130693-82-2
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material
Dorzolamide hydrochloride is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. Distributed throughout many cells and tissues, various carbonic anhydrases play important roles in mineral and metabolic homeostasis.
pharmaceutical raw material for the manufacturing of carbonic anhydrase inhibitor productsactive pharmaceutical ingredient in formulations for the management of elevated intraocular pressure
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
StrongSame Parent
Dorzolamide
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SimilarStructure SimilarSimilarity 0.78
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2H-Pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4S,12aR)-
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pharmaceutical raw material
Referencestereoisomer of
(+/-)-(cis)-dorzolamide hydrochloride
CAS120279-37-0
pharmaceutical raw material
Referencesame scaffold
N-[(4S,6S)-6-Methyl-7,7-dioxo-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl]acetamide
CAS147200-03-1
pharmaceutical intermediate
Safety Reference
Warning
H302Harmful if swallowed
H373May cause damage to organs through prolonged or repeated exposure
Identifiers
IUPAC Name
(4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide;hydrochloride
InChIKey
OSRUSFPMRGDLAG-QMGYSKNISA-N
SMILES
CCN[C@H]1C[C@@H](S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)C.Cl
Synonyms (36)
- Dorzolamide for system suitability, European Pharmacopoeia (EP)
- Dorzolamide hydrochloride (JP18/USP)
- Dorzolamide hydrochloride [EP monograph]
- Dorzolamide hydrochloride, European Pharmacopoeia (EP)
- Dorzolamide hydrochloride, United States Pharmacopeia (USP)
- Cosopt
- DORZOLAMIDE HYDROCHLORIDE
- Dorzolamide HCI
- Dorzolamide HCl
- Dorzolamide PF
- Dorzolamide hydrochloride CRS
- Dorzolomide hydrochloride
- L-671,152
- L671152;MK507
- Trusopt
- Trusopt (TN)
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