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Home/Compounds/API/Icatibant
C59H89N19O13S
1304.5 g/mol
API

Icatibant

CAS130308-48-4
Category
API
Compound Class
Peptide
Primary Use
Pharmaceutical Raw Material

Icatibant is a synthetic decapeptide compound used as a pharmaceutical raw material. It is a bradykinin B2 receptor antagonist employed in the manufacturing of medications for hereditary angioedema.

pharmaceutical manufacturingresearch compound for bradykinin receptor studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Icatibant acetate

CAS138614-30-9

pharmaceutical raw material

ReferenceSame Category

Izilendustat

CAS1303512-02-8

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Bismuth subnitrate

CAS1304-85-4

pharmaceutical raw material

ReferenceSame Category

Ozanimod

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pharmaceutical raw material

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Dorzolamide hydrochloride

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pharmaceutical raw material

Identifiers
IUPAC Name

(2S)-2-[[(2S,3aS,7aS)-1-[(3R)-2-[(2S)-2-[[(2S)-2-[[2-[[(2S,4R)-1-[(2S)-1-[(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]-4-hydroxypyrrolidine-2-carbonyl]amino]acetyl]amino]-3-thiophen-2-ylpropanoyl]amino]-3-hydroxypropanoyl]-3,4-dihydro-1H-isoquinoline-3-carbonyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid

InChIKey

QURWXBZNHXJZBE-SKXRKSCCSA-N

SMILES

C1CC[C@H]2[C@@H](C1)C[C@H](N2C(=O)[C@H]3CC4=CC=CC=C4CN3C(=O)[C@H](CO)NC(=O)[C@H](CC5=CC=CS5)NC(=O)CNC(=O)[C@@H]6C[C@H](CN6C(=O)[C@@H]7CCCN7C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](CCCN=C(N)N)N)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O

Synonyms (18)
  • Firazyr
  • HOE 140 TFA
  • HOE-140 (Icatibant)
  • Icatibant
  • Icatibant (Standard)
  • Icatibant HOE 140
  • icatibant-acetate
  • icatibanto
  • icatibantum