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Home/Compounds/Pharmaceutical Intermediate/(4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester
C13H24O5
260.33 g/mol
Pharmaceutical IntermediateWarning

Tert-butyl 2-[(4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate

CAS124655-09-0EC432-960-5
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate

This compound is a pharmaceutical intermediate primarily used in the manufacturing of rosuvastatin, a statin medication. It features a chiral dioxane ring with hydroxymethyl and ester functional groups.

Pharmaceutical intermediate for rosuvastatin manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.76

Tert-Butyl [(4R,6S)-6-(chloromethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate

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SimilarStructure SimilarSimilarity 0.72

Tert-butyl 2-[(4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate

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SimilarStructure SimilarSimilarity 0.72

Tert-Butyl (4R-cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetate

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ApplicationSame Use

Tert-Butyl rosuvastatin

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pharmaceutical intermediate

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Methyl 5-chloropyrazine-2-carboxylate

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ReferenceSame Category

N-Boc-D-tert-leucine

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pharmaceutical intermediate

Safety Reference

Harmful
Harmful
Warning
H302Harmful if swallowed

Customs Tariff Classification

The international HS code for Tert-butyl 2-[(4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate (CAS 124655-09-0) is 2932.99.

HS code (international, 6-digit)

2932.99

EU CN code (8-digit)

2932 99 00

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

tert-butyl 2-[(4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate

InChIKey

CFRUAOXMCVQMFP-ZJUUUORDSA-N

SMILES

CC1(O[C@H](C[C@H](O1)CO)CC(=O)OC(C)(C)C)C

Synonyms (16)

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