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Home/Compounds/Pharmaceutical Intermediate/4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidinyl-5-yl-formyl
C16H18FN3O3S
351.4 g/mol
Pharmaceutical Intermediate

N-[4-(4-Fluorophenyl)-5-formyl-6-(1-methylethyl)-2-pyrimidinyl]-N-methylmethanesulfonamide

CAS147118-37-4
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a pharmaceutical intermediate specifically used in the manufacturing process of rosuvastatin, a lipid-lowering medication. It serves as a key building block in the synthesis of this statin drug.

Pharmaceutical intermediate for rosuvastatin production

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

N-[4-(4-Fluorophenyl)-5-formyl-6-(1-methylethyl)-2-pyrimidinyl]-N-methylmethanesulfonamide

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SimilarStructure SimilarSimilarity 0.79

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ApplicationSame Use

Methyl 5-chloropyrazine-2-carboxylate

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pharmaceutical intermediate

ApplicationSame Use

Tert-Butyl rosuvastatin

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pharmaceutical intermediate

ApplicationSame Use

2,3,3-trimethylbenzoindolenine

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pharmaceutical intermediate

ApplicationSame Use

Rosuvastatin ethyl ester

CAS851443-04-4

pharmaceutical intermediate

ReferenceSame Category

Methyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidine-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(6E)-heptanoate

CAS147118-38-5

pharmaceutical intermediate

ReferenceSame Category

Methyl (+)-(3R)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesulfonylamino)pyrimidin-5-yl]-3-hydroxy-5-oxo-(6E)-heptenoate

CAS147118-39-6

pharmaceutical intermediate

Identifiers
IUPAC Name

N-[4-(4-fluorophenyl)-5-formyl-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide

InChIKey

WOCOTUDOVSLFOB-UHFFFAOYSA-N

SMILES

CC(C)C1=NC(=NC(=C1C=O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C

Synonyms (19)
  • Cyclo-pptl(Z)TP
  • Rosuvastatin Formyl Impurity
  • Rosuvastatin Impurity 106
  • Rosuvastatin calcium Z8