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Home/Compounds/API/Ruxolitinib phosphate
C17H21N6O4P
404.4 g/mol
APIDanger

Ruxolitinib phosphate

CAS1092939-17-7
Category
API
Compound Class
Other
Primary Use
Pharmaceutical Raw Material

Ruxolitinib phosphate is a phosphate salt of ruxolitinib, formed by reacting ruxolitinib with one equivalent of phosphoric acid. It functions as a non-specific protein-tyrosine kinase inhibitor and is used as an antineoplastic agent in pharmaceutical manufacturing.

antineoplastic agentEC 2.7.10.2 inhibitor

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Ruxolitinib hydrochloride

CAS1912373-07-9

pharmaceutical raw material

StrongSame Parent

Ruxolitinib

CAS941678-49-5

pharmaceutical raw material

StrongSame Parent

(betaR)-beta-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile maleate

CAS1092939-15-5

research compound

ReferenceSame Category

(3R,5R)-Rosuvastatin

CAS1094100-06-7

pharmaceutical raw material

ReferenceSame Category

Methadone hydrochloride

CAS1095-90-5

pharmaceutical raw material

ReferenceSame Category

4-(2-(Benzyl(methyl)amino)-1-hydroxyethyl)benzene-1,2-diol

CAS1095714-91-2

pharmaceutical raw material

ReferenceSame Category

Cis-loperamide oxide

CAS109572-89-6

pharmaceutical raw material

Referencestereoisomer of

Deuruxolitinib phosphate

CAS2147706-60-1

pharmaceutical raw material

Safety Reference

Toxic
Toxic
Harmful
Harmful
Health Hazard
Health Hazard
Environmental Hazard
Environmental Hazard
Danger
H301Toxic if swallowed
H302Harmful if swallowed
H361Suspected of damaging fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects

Customs Tariff Classification

The international HS code for Ruxolitinib phosphate (CAS 1092939-17-7) is 2933.59.

HS code (international, 6-digit)

2933.59

EU CN code (8-digit)

2933 59 95

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile;phosphoric acid

InChIKey

JFMWPOCYMYGEDM-XFULWGLBSA-N

SMILES

C1CCC(C1)[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O

Synonyms (25)
  • Ruxolitinib phosphate (JAN/USAN)
  • 1092939-17-7 (phosphate)
  • INCB 018424
  • INCB-018424 Salt
  • INCB-018424 phosphate
  • INCB-18424 PHOSPHATE
  • Jakafi
  • Jakafi (TN)
  • Jakavi
  • Jakavi (TN)
  • Opzelura (TN)
  • Ruxolitinib phosphate
  • Ruxolitinib phosphate salt
  • ruxolitinib (as phosphate)
  • ruxolitinib monophosphate

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