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Home/Compounds/API/Momelotinib
C23H22N6O2
414.5 g/mol
APIWarning

Cyt387

CAS1056634-68-4
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Momelotinib, also known as Cyt387, is an ATP-competitive inhibitor of Janus kinases 1 and 2 (JAK1/JAK2). It is a benzamide derivative used as an active pharmaceutical ingredient in the production of treatments for myelofibrosis.

Pharmaceutical raw material for myelofibrosis therapyJAK1/JAK2 inhibitor in drug manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Momelotinib dihydrochloride

CAS1380317-28-1

pharmaceutical raw material

StrongSame Parent

Momelotinib dihydrochloride monohydrate

CAS1841094-17-4

pharmaceutical raw material

ReferenceSame Category

Acrivastine isomer Z

CAS1057138-89-2

pharmaceutical raw material

ReferenceSame Category

(-)(3S,4R)-4-(4-fluorophenyl)-3-(3,4-methylenedioxy-phenoxymethyl)-N-benzylpiperidine hydrochloride

CAS105813-13-6

pharmaceutical raw material

ReferenceSame Category

Nateglinide

CAS105816-04-4

pharmaceutical raw material

ReferenceSame Category

Ent-Nateglinide

CAS105816-05-5

pharmaceutical raw material

Referencesame scaffold

4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzoic acid

CAS945749-71-3

pharmaceutical intermediate

Safety Reference

Harmful
Harmful
Warning
H302Harmful if swallowed
Identifiers
IUPAC Name

N-(cyanomethyl)-4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]benzamide

InChIKey

ZVHNDZWQTBEVRY-UHFFFAOYSA-N

SMILES

C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N

Synonyms (22)
  • EX-A260
  • Momelotinib (USAN/INN)
  • CYT 11387
  • CYT387,CYT 11387
  • Cyt387
  • Momelotinib
  • Momelotinib (CYT387)
  • Momelotinib (CYT387,CYT-387)
  • Ojjaara
  • Omjjara
  • SDCCGSBI-0654405.P001
  • momelotinibum