C23H19N3O2
369.4 g/mol
APIDanger
Tivantinib
CAS1000873-98-2
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Tivantinib is an experimental small molecule anti-cancer compound. It is a bisindolylmaleimide that binds to the dephosphorylated MET kinase in vitro and is being investigated as a highly selective c-Met inhibitor in clinical trials.
research compound for c-Met inhibition studiespharmaceutical raw material for oncology research
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Safety Reference
Danger
H360May damage fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
Identifiers
IUPAC Name
(3R,4R)-3-(1-azatricyclo[6.3.1.04,12]dodeca-2,4,6,8(12)-tetraen-3-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione
InChIKey
UCEQXRCJXIVODC-PMACEKPBSA-N
SMILES
C1CC2=C3C(=CC=C2)C(=CN3C1)[C@H]4[C@@H](C(=O)NC4=O)C5=CNC6=CC=CC=C65
Synonyms (20)
- ARQ-197
- TIV
- Tivantinib (JAN/USAN/INN)
- (rel)-Tivantinib
- ARQ 197 (Tivantinib)
- ARQ-197,Tivantinib, ARQ197
- ARQ197; ARQ-197;Tivantinib
- SDCCGSBI-0654487.P001
- Tivantinib
- Tivantinib (ARQ 197)
- c-Met Inhibitor ARQ 197
- tivantinibum
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