Home/Compounds/Pharmaceutical Intermediate/(6-(6-benzamido-9H-purin-9-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate
C38H37ClN7O4P
722.2 g/mol
Pharmaceutical IntermediateWarning
(6-(6-benzamido-9H-purin-9-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate
CAS956139-18-7EC851-165-8
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate
This compound is a phosphorodiamidate morpholino oligomer (PMO) monomer, a synthetic building block used in the production of Morpholino oligonucleotides. Its backbone consists of morpholine rings linked by phosphorodiamidate groups, rather than the sugar-phosphate backbone found in natural nucleic acids.
PMO monomer for oligonucleotide synthesisResearch reagent for gene expression modulation in molecular biology
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 956139-18-7
Related Compounds
ReferenceSame Category
((2S,6R)-6-(2-Isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate
CAS956139-25-6
pharmaceutical intermediate
ReferenceSame Category
(6-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate)
CAS956139-30-3
pharmaceutical intermediate
ReferenceSame Category
5-Methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid
CAS956317-36-5
pharmaceutical intermediate
ReferenceSame Category
2'-Deoxythymidine-5'-diphosphate trisodium salt
CAS95648-78-5
pharmaceutical intermediate
Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H410Very toxic to aquatic life with long lasting effects
Identifiers
IUPAC Name
N-[9-[(2R,6S)-6-[[chloro(dimethylamino)phosphoryl]oxymethyl]-4-tritylmorpholin-2-yl]purin-6-yl]benzamide
InChIKey
HRNHOEBQNIMEGD-RJFDGRJRSA-N
SMILES
CN(C)P(=O)(OC[C@@H]1CN(C[C@@H](O1)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)C(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)Cl
Synonyms (10)
- MORPHOLINO A SUBUNIT
- PMO-A(Bz) Monomer
- PMO-BzA