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Home/Compounds/Pharmaceutical Intermediate/N'-[(1,1-Dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N'-methyl-L-lysine
C27H34N2O6
482.6 g/mol
Pharmaceutical IntermediateWarning

FMOC-LYS(ME,BOC)-OH

CAS951695-85-5
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

This compound is a protected derivative of lysine, featuring both a 9-fluorenylmethoxycarbonyl (Fmoc) group on the alpha-amino group and a methyl-tert-butoxycarbonyl (Me,Boc) protected side-chain. It is primarily used as a building block in solid-phase peptide synthesis, enabling the sequential assembly of peptides with orthogonal protection schemes.

Building block for solid-phase peptide synthesisReagent for the preparation of modified peptides containing N-methyl-lysine residues

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.82

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SimilarStructure SimilarSimilarity 0.75

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Safety Reference

Environmental Hazard
Environmental Hazard
Warning
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
Identifiers
IUPAC Name

(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]hexanoic acid

InChIKey

JHMSFOFHTAYQLS-QHCPKHFHSA-N

SMILES

CC(C)(C)OC(=O)N(C)CCCC[C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Synonyms (12)
  • FMOC-LYS(ME,BOC)-OH
  • Fmoc-Lys(Boc,Me)-OH