C9H11F2N3O4
263.2 g/mol
APIDanger
Gemcitabine
CAS95058-81-4EC619-100-6
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Gemcitabine is a fluorinated nucleoside analog that inhibits ribonucleotide reductase and DNA synthesis. It is used as a pharmaceutical raw material in the manufacturing of anti-cancer medications and as a research compound in oncology studies.
pharmaceutical manufacturingantineoplastic researchradiosensitization research
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 95058-81-4
Related Compounds
StrongSame Parent
Gemcitabine hydrochloride
CAS122111-03-9
pharmaceutical raw material
ReferenceSame Category
Quizartinib
CAS950769-58-1
pharmaceutical raw material
ReferenceSame Category
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CAS951-77-9
pharmaceutical raw material
ReferenceSame Category
Nemonoxacin malate
CAS951163-60-3
pharmaceutical raw material
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pharmaceutical raw material
Safety Reference
Danger
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H340May cause genetic defects
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H373May cause damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects
Identifiers
IUPAC Name
4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
InChIKey
SDUQYLNIPVEERB-QPPQHZFASA-N
SMILES
C1=CN(C(=O)N=C1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F
Synonyms (46)
- Gemcitabina [INN-Spanish]
- Gemcitabine (USAN/INN)
- Gemcitabinum [INN-Latin]
- 188011, LY
- 2',2'-DFDC
- 2',2'-DiF-dC
- 2',2'-Difluorodeoxycytidine
- 2'-deoxy-2'-difluorocytidine
- 2vpp
- 4pd5
- 95058-81-4 (free base)
- DFdCyd
- Difluorodeoxycytidine
- Folfugem
- Gamcitabine
- Gecitabine base
- GemLip
- Gemcel
- Gemcitabina
- Gemcitabine (Standard)
- Gemcitabine base
- Gemcitabine free base
- Gemcitabinum
- Gemzar (hydrochloride)
- Hydrochloride, Gemcitabine
- Zefei
- dFdC
- gemcitabine
- gemcitabine (Gemzar)
- gemicitabine