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Home/Compounds/Research Reagent/5-Carboxyfluorescein N-succinimidyl ester
C25H15NO9
473.4 g/mol
Research ReagentWarning

5-Carboxyfluorescein N-succinimidyl ester

CAS92557-80-7
Category
Research Reagent
Compound Class
Ester
Primary Use
Research Compound

5-Carboxyfluorescein N-succinimidyl ester is a cell-permeable fluorescent dye that reacts with primary amines, commonly used in cell proliferation research. Its acetate-modified form, CFDA-SE, enhances cell permeability at the cost of fluorescence until intracellular activation.

Labeling of live cells for proliferation trackingFlow cytometry-based cell division analysisAmine-reactive fluorescent probe for biomolecule conjugation

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

(2,5-dioxopyrrolidin-1-yl) 3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-carboxylate

InChIKey

GECIDMICWWDIBO-UHFFFAOYSA-N

SMILES

C1CC(=O)N(C1=O)OC(=O)C2=CC3=C(C=C2)C4(C5=C(C=C(C=C5)O)OC6=C4C=CC(=C6)O)OC3=O

Synonyms (11)
  • 5-Carboxyfluorescein-NHS
  • 5-FAM SE
  • CFSE;