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Home/Compounds/API/Nilotinib hydrochloride monohydrate
C28H25ClF3N7O2
584 g/mol
APIWarning

Nilotinib hydrochloride monohydrate

CAS923288-90-8
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Nilotinib hydrochloride monohydrate is the monohydrate monohydrochloride salt form of nilotinib, an orally bioavailable aminopyrimidine-derivative tyrosine kinase inhibitor. It is a pharmaceutical raw material used in the manufacturing of active pharmaceutical ingredients for cancer research.

Pharmaceutical raw material for API manufacturingResearch compound for Bcr-Abl kinase inhibition studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Nilotinib

CAS641571-10-0

pharmaceutical raw material

ReferenceSame Category

Iodixanol

CAS92339-11-2

pharmaceutical raw material

ReferenceSame Category

Simeprevir

CAS923604-59-5

pharmaceutical raw material

ReferenceSame Category

(7S-cis)-9-Acetyl-9-amino-7-[(2-deoxy-alpha-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-5,12-naphthacenedione

CAS92395-36-3

pharmaceutical raw material

ReferenceSame Category

Ursodeoxycholylglycine sodium

CAS92411-07-9

pharmaceutical raw material

Referencesame scaffold

N-Nitrosonilotinib

CAS2925306-68-7

pharmaceutical intermediate

Safety Reference

Harmful
Harmful
Environmental Hazard
Environmental Hazard
Warning
H302Harmful if swallowed
H317May cause an allergic skin reaction
H410Very toxic to aquatic life with long lasting effects

Customs Tariff Classification

The international HS code for Nilotinib hydrochloride monohydrate (CAS 923288-90-8) is 2933.59.

HS code (international, 6-digit)

2933.59

EU CN code (8-digit)

2933 59 95

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide;hydrate;hydrochloride

InChIKey

YCBPQSYLYYBPDW-UHFFFAOYSA-N

SMILES

CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.O.Cl

Synonyms (27)
  • NILOTINIB HYDROCHLORIDE MONOHYDRATE (EP MONOGRAPH)
  • 641571-10-0, Nilotinib
  • 923288-90-8 (HCl hydrate)
  • AMN107 HCl hydrate
  • Nilotinib (as hydrochloride)
  • Nilotinib HCl hydrate
  • Nilotinib HCl monohydrate
  • Tasigna (TN)

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