C28H25ClF3N7O2
584 g/mol
APIWarning
Nilotinib hydrochloride monohydrate
CAS923288-90-8
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Nilotinib hydrochloride monohydrate is the monohydrate monohydrochloride salt form of nilotinib, an orally bioavailable aminopyrimidine-derivative tyrosine kinase inhibitor. It is a pharmaceutical raw material used in the manufacturing of active pharmaceutical ingredients for cancer research.
Pharmaceutical raw material for API manufacturingResearch compound for Bcr-Abl kinase inhibition studies
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
Sourcing or supplying this compound?
List your inventory or post a purchase request
CAS 923288-90-8
Related Compounds
StrongSame Parent
Nilotinib
CAS641571-10-0
pharmaceutical raw material
ReferenceSame Category
Iodixanol
CAS92339-11-2
pharmaceutical raw material
ReferenceSame Category
Simeprevir
CAS923604-59-5
pharmaceutical raw material
ReferenceSame Category
(7S-cis)-9-Acetyl-9-amino-7-[(2-deoxy-alpha-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-5,12-naphthacenedione
CAS92395-36-3
pharmaceutical raw material
ReferenceSame Category
Ursodeoxycholylglycine sodium
CAS92411-07-9
pharmaceutical raw material
Referencesame scaffold
N-Nitrosonilotinib
CAS2925306-68-7
pharmaceutical intermediate
Safety Reference
Warning
H302Harmful if swallowed
H317May cause an allergic skin reaction
H410Very toxic to aquatic life with long lasting effects
Identifiers
IUPAC Name
4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide;hydrate;hydrochloride
InChIKey
YCBPQSYLYYBPDW-UHFFFAOYSA-N
SMILES
CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.O.Cl
Synonyms (27)
- NILOTINIB HYDROCHLORIDE MONOHYDRATE (EP MONOGRAPH)
- 641571-10-0, Nilotinib
- 923288-90-8 (HCl hydrate)
- AMN107 HCl hydrate
- Nilotinib (as hydrochloride)
- Nilotinib HCl hydrate
- Nilotinib HCl monohydrate
- Tasigna (TN)